Liriano makes his return after a month-long absence with a strained left oblique. He has one win in his last 17 regular-season starts. He lasted longer than five innings in only one of his last nine starts before landing on the DL.
Cueto went 6 1/3 innings in a win over the Cubs on Tuesday, allowing two runs on six hits, walking one and striking out four. The All-Star is 15-4 with a 2.18 ERA in 24 career starts against the Pirates, including four complete games.